CPB Weaning — Separation From Cardiopulmonary Bypass
Checklist-driven transition from mechanical to native circulation: rewarm, ventilate, de-air, TOE, protamine, inotropy, trial off, decannulate.
CPB weaning is a deliberate, checklist-gated transition from mechanical to native circulation, gated by rewarming, ventilation, de-airing, TOE, hemostasis, inotropy, and a graded flow reduction before decannulation.
If you forget
HEADLINE: Run the WEAN checklist before touching pump flow — reheat ≥36 °C, vents off, TOE in, inotropes loaded, ABG/K+/Ca2+ correct, protamine ready.
Board trap
Key numbers
- ACT target ≥480 s on CPB
- Protamine 0.8–1.0 × initial heparin dose (1.3 ratio → bleeding)
- Rewarm to ≥36 °C core before weaning
- Trial CPB flow 1–2 L/min before decannulation
- VA-ECMO wean: 0.5–1 L/min q5–15 min rapid or q2–4 h standard
Uri Rozen, MD — Licensed Physician, Israel
Source guidelines: EACTS EACTA EBCP CPB Fulltext 2019 · EACTS EACTA EBCP CPB Fulltext 2019 · EACTS EACTA EBCP CPB Fulltext 2019 · EACTS EACTA EBCP CPB Fulltext 2019
Re-review cadence: 12 months from reviewed date.
Related on BoardsBridge
Card ID: cpb-weaning · Path: aba.cardiac.cardiopulmonary-bypass.cpb-weaning
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