BoardsBridge
Clinical Disease
cardiac
High-impact pattern

Eisenmenger Syndrome in Adult Congenital Heart Disease (ACHD) — Anesthetic Management

Irreversible reversal of a left-to-right intracardiac shunt once pulmonary vascular resistance exceeds systemic — high perioperative risk during noncardiac surgery.

Eisenmenger syndrome is the irreversible reversal of a left-to-right intracardiac shunt (VSD/ASD/PDA) to right-to-left once pulmonary vascular resistance exceeds systemic vascular resistance, producing chronic cyanosis, erythrocytosis, and high perioperative risk for noncardiac surgery.

If you forget

Eisenmenger = PVR > SVR → R→L shunt → cyanosis; Qp/Qs falls below 1.

Board trap
"Eisenmenger patient desaturates after induction — first move?" Correct airway/equipment faults and reversible increases in PVR, restore SVR, and administer oxygen when clinically indicated; if inadequate pulmonary blood flow makes room air life-threatening, discuss oxygen administration with the interventional cardiologist.

Key numbers

  • Qp/Qs < 1 = net right-to-left; Qp/Qs > 1 = net left-to-right; Qp/Qs = 1 = balanced (Miller's Ch. 73).
  • Intraop BP goal: MAP ≥60–65 mm Hg or SBP ≥90 mm Hg (2024 AHA/ACC perioperative guideline).
  • Pressure-overload physiology takes 'years' to cause ventricular dysfunction/failure in isolated lesions (Miller's Ch. 73).
  • Vasodilators in shunting physiology may decrease both PVR and SVR, increase extrapulmonary shunting, and further reduce pulmonary blood flow (Miller's Ch. 75).
Reviewed Oct 8, 2026 for clinical accuracy by BoardsBridge Editorial Process

Uri Rozen, MD — Licensed Physician, Israel

Source guidelines: Millers Anesthesia 10 Ch73 Anesthesia FOR Pediatric Cardiac Surgery · AHA ACC Perioperative Cardiovascular 2024 · Millers Anesthesia 10 Ch75 Pediatric AND Neonatal Critical Care · Millers Anesthesia 10 Ch50 Anesthesia FOR Cardiac Surgical Procedures

Re-review cadence: 12 months from reviewed date.

Drill this as a SOE stem →

Related on BoardsBridge

Card ID: eisenmenger · Path: aba.cardiac.congenital-adult.eisenmenger

Educational reference only. Reviewed for clinical accuracy against current authoritative guidelines. Not a substitute for clinical judgment. See editorial process and the sitemap entry for this card.