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Hypertrophic Cardiomyopathy (HCM) — Perioperative Anesthetic Management

Dynamic LVOT obstruction: keep the ventricle full, slow, and vasoconstricted

HCM is a dynamic, preload- and afterload-dependent LVOT obstruction — anesthetic goals are full preload, slow heart rate, maintained afterload, and avoidance of inotropes or vasodilators.

If you forget

FULL, SLOW, TIGHT: keep LV full, rate slow, SVR up — opposite of AS

Board trap
Question gives a patient on chronic metoprolol undergoing cholecystectomy — the trap is 'hold the beta-blocker preop.' Wrong. AHA/ACC 2024 says CONTINUE beta-blockers and non-DHP CCBs without interruption in HCM.

Key numbers

  • MAP goal ≥ 60-65 mm Hg (AHA/ACC 2024 perioperative target)
  • Systolic BP goal ≥ 90 mm Hg intraop
  • Phenylephrine: 50-200 mcg IV bolus, then 10-100 mcg/min infusion
  • Vasopressin: 0.5-2 U IV bolus, then 0.04 U/min infusion
  • Esmolol: 0.5 mg/kg IV bolus, then 50-200 mcg/kg/min
  • Mid-to-late systolic late-peaking velocity curve on Doppler = dynamic LVOT obstruction
Reviewed Sep 24, 2026 for clinical accuracy by BoardsBridge Editorial Process

Uri Rozen, MD — Licensed Physician, Israel

Source guidelines: AHA ACC Perioperative Cardiovascular 2024 · AHA ACC Perioperative Cardiovascular 2024 · AHA ACC Perioperative Cardiovascular 2024 · ASE EACVI Aortic Stenosis 2017

Re-review cadence: 12 months from reviewed date.

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Related on BoardsBridge

Card ID: hcm · Path: aba.cardiac.heart-failure-cardiomyopathy.hcm

Educational reference only. Reviewed for clinical accuracy against current authoritative guidelines. Not a substitute for clinical judgment. See editorial process and the sitemap entry for this card.