Aneurysmal SAH Vasospasm & Delayed Cerebral Ischemia
Recognition, prophylaxis, and ICU management of cerebral vasospasm and DCI days 3-14 after aneurysmal subarachnoid hemorrhage
Cerebral vasospasm is delayed arterial narrowing of the circle of Willis 3-14 days after aneurysmal SAH, producing BP-dependent neurologic deficits and progressing to delayed cerebral ischemia (DCI) if untreated; prophylaxis centers on oral nimodipine, euvolemia, and avoidance of hypotension and hyponatremia.
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Headline: Nimodipine 60 mg PO/NG q4h x 21 days is the only proven DCI prophylaxis — start early and tolerate mild hypotension.
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Key numbers
- Nimodipine 60 mg PO/NG q4h x 21 days (360 mg/day total)
- Nicardipine IV 0.075-0.15 mg/kg/hr when PO nimodipine not tolerated
- Vasospasm window: days 3-14 post-SAH; peak DCI day 4-10
- Modified Triple-H hemodilution target Hct 30-35%
- TCD sensitivity 90%, NPV 92% for DCI prediction
- Antiseizure medication duration ≤7 days for onset seizures
Uri Rozen, MD — Licensed Physician, Israel
Source guidelines: SNACC Neuroanesthetic Emergencies 2020 · AHA SAH 2023
Re-review cadence: 12 months from reviewed date.
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Card ID: sah-vasospasm · Path: aba.critical-care.neurocritical-care.sah-vasospasm
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