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Monitoring
monitoring
High-impact pattern

Serial Acid-Base & Ketone Monitoring

Trending β-hydroxybutyrate, anion gap, and bicarbonate during DKA, AKA, and perioperative metabolic stress

Serial β-hydroxybutyrate and venous blood gas trending every 1-2 hours guides DKA/AKA insulin titration; resolution requires β-OHB <0.6 mmol/L AND closed anion gap, not normalized glucose.

If you forget

β-hydroxybutyrate > acetoacetate in DKA — measure β-OHB, not urine strips

Board trap
Resident stops insulin when glucose normalizes — wrong. Insulin must continue (with D5) until AG closes and β-OHB <0.6; stopping on euglycemia alone causes DKA relapse.

Key numbers

  • β-OHB <0.6 mmol/L = ketonemia resolved
  • Anion gap normal ≤12 mEq/L
  • Insulin infusion 0.1 U/kg/hr (no bolus)
  • Add D5 when glucose <200 mg/dL
  • Correct Na+ no faster than 10 mEq/L per 24 h
  • K+ <3.3 mEq/L = hold insulin
Reviewed Sep 15, 2026 for clinical accuracy by BoardsBridge Editorial Process

Uri Rozen, MD — Licensed Physician, Israel

Source guidelines: ASA SCA Perioperative TEE 2010 · ASA SCA Perioperative TEE 2010

Re-review cadence: 12 months from reviewed date.

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Related on BoardsBridge

Card ID: serial-acid-base-ketones · Path: aba.monitoring.laboratory-trending.serial-acid-base-ketones

Educational reference only. Reviewed for clinical accuracy against current authoritative guidelines. Not a substitute for clinical judgment. See editorial process and the sitemap entry for this card.